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Nathaniel A Brown Selected Research

Telbivudine

2/20092-Year GLOBE trial results: telbivudine Is superior to lamivudine in patients with chronic hepatitis B.
2/2008Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial.
12/2007Telbivudine versus lamivudine in patients with chronic hepatitis B.
12/2007Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial.
12/2007Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment.
7/2006Pharmacokinetics of telbivudine in healthy subjects and absence of drug interaction with lamivudine or adefovir dipivoxil.
5/2006Pharmacokinetics of telbivudine in subjects with various degrees of hepatic impairment.
3/2006Pharmacokinetics of telbivudine following oral administration of escalating single and multiple doses in patients with chronic hepatitis B virus infection: pharmacodynamic implications.
8/2005A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B.
9/2004A dose-finding study of once-daily oral telbivudine in HBeAg-positive patients with chronic hepatitis B virus infection.

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Nathaniel A Brown Research Topics

Disease

12Chronic Hepatitis B
02/2009 - 07/2002
2Infections
06/2009 - 03/2006
2Hepatitis B
06/2009 - 12/2007
2Liver Diseases (Liver Disease)
02/2008 - 05/2006
1Chronic Hepatitis C
06/2009
1Hepatitis C
06/2009
1Liver Neoplasms (Liver Cancer)
06/2009
1Liver Failure
06/2009
1Viremia
02/2009
1Chronic Hepatitis (Chronic Active Hepatitis)
12/2007
1Chronic Kidney Failure (Chronic Renal Failure)
12/2007

Drug/Important Bio-Agent (IBA)

10TelbivudineFDA Link
02/2009 - 09/2004
8Antiviral Agents (Antivirals)IBA
06/2009 - 09/2002
8Hepatitis B e AntigensIBA
02/2009 - 07/2002
8Lamivudine (Epivir)FDA Link
02/2009 - 07/2002
3NucleosidesIBA
06/2009 - 05/2006
2adefovir dipivoxil (Hepsera)FDA Link
12/2007 - 07/2006
2InterferonsIBA
06/2003 - 07/2002
1NucleotidesIBA
12/2007
1adefovirIBA
12/2007
1CreatinineIBA
12/2007
1Pharmaceutical PreparationsIBA
03/2006
1Alanine Transaminase (SGPT)IBA
07/2002
1DNA (Deoxyribonucleic Acid)IBA
07/2002

Therapy/Procedure

6Therapeutics
06/2009 - 09/2002
1Renal Dialysis (Hemodialysis)
12/2007
1Oral Administration
03/2006
1Liver Transplantation
09/2002